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You cannot randomize. What is the strongest causal claim you can still make?

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Answer

  • One conditional on an assumption you state explicitly, which is the honest form of every observational causal claim.
  • Begin by drawing the assumed causal structure, because which variables to adjust for is a question about that structure, not about which improve fit; conditioning on a collider or a mediator introduces bias rather than removing it.
  • If you can argue that all confounders are measured, adjustment or matching gives an effect estimate under that assumption.
  • Stronger designs exploit structure instead: a difference-in-differences comparison if you have pre-period data and a plausible parallel trend, an instrumental variable if something shifts treatment without affecting the outcome directly, or a regression discontinuity if assignment follows a threshold.
  • Then test the assumption, with placebo outcomes and pre-trend checks, and report sensitivity to unmeasured confounding.
Check yourself — multiple choice
  • None, only randomization allows causal claims
  • A claim conditional on a stated identification assumption: draw the causal structure, adjust for confounders not colliders, prefer difference-in-differences, instruments or discontinuities, then run placebo and sensitivity checks
  • Correlation is enough with big data
  • Add every available control variable

Observational causality rests on an explicit identification assumption plus falsification and sensitivity analysis.

#causal-inference#quasi-experimental

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